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So we can excrete HUGE amounts of B12 in a short time if it is extraneous to the amount we currently need

Baseline (before starting GLP-1 or supplements): 25-hydroxyvitamin D (target: 30-50 ng/mL) Vitamin B12 (target: above 400 pg/mL) Serum iron, ferritin, and TIBC Serum magnesium Serum zinc Complete metabolic panel CBC (to check for anemia) Follow-up testing at 3 and 6 months: Repeat all baseline labs Add: body composition measurement (DEXA scan is gold standard) to track lean mass vs fat mass changes Assess supplement adherence and adjust doses based on results The cost of basic nutritional bloodwork is minimal compared to the cost of undiagnosed deficiencies

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For further coverage of this issue see the following references (6, 30, 35, 99, 100)

CAS number: 2023788-19-2

Oral potassium supplementation (e.g., Sando-K or Kay-Cee-L) is first-line for mild to moderate hypokalaemia