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Some patients maintain more weight loss, especially those who made substantial lifestyle changes during treatment

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For example, participants in the trials reported side effects that were generally consistent with previous studies, such as gastrointestinal symptoms, which are one of the main reasons that can lead to discontinuation of the drugs

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However, the response might be more accurately described as a 'modified T H 2-cell response', with high IL-10 and IgG4 antibody isotypes, and low IgE reactions