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After 5 weeks of treatment with once-daily subcutaneous administration of liraglutide 1.8 mg and 3.0 mg, estimated reductions in body weight were 2.1 kg and 2.5 kg, respectively, vs
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One phase IIb clinical trial administered setmelanotide to obese participants with heterozygous MC4R deficiency and obese controls over 28 days, observing a placebo-adjusted weight loss of 2.6 kg and 4.0 kg respectively [98]
Rebound weight gain after semaglutide is common but not inevitable
Focus on nutrient-dense foods that provide essential vitamins, minerals, and macronutrients in smaller volumes
