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Histopathological analysis involved fixing left lung lobes in 10% neutral formalin, embedding in paraffin, sectioning into 4 m thick sections, and staining with hematoxylin and eosin (H&E)
In comparison, an emerging treatment with potential therapeutic application, in the form of a pentadecapeptide known as BPC 157 (body protection compound), appears to be somewhat unrestricted by the limitations seen in previous therapies
The combination approach of targeting two separate pathways produces results competitive with even the most effective single-agent therapies currently available
Frontiers in Aging Neuroscience, 14 , 888292
References: He, B., Wang, F., & Qu, L
Other factors expressed by astrocytes, including VEGF, glial cell derived neurotrophic factor (GDNF), and angiopoietin-1, mediate angiogenesis and recruitment of TJ proteins, contributing to BBB development and maintenance (Cabezas et al., 2014
