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Take home message Feeling tired is a common side effect of Wegovy, affecting nearly half of patients in the first month of treatment
The well-documented disconnect between biomarker modulation and clinical outcomes in neurodegenerative diseases illustrated most starkly by the history of anti-amyloid therapies means that statistically significant reductions in p-tau or YKL-40 do not constitute evidence of meaningful clinical benefit
You could see visible improvements in skin and hair appearance within 6-8 weeks of daily use
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Furthermore, the data set is representative only of people with health insurance
As a general principle, it takes approximately five half-lives for a medication to be considered essentially eliminated from the body (representing about 97% clearance)
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