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Currently, endpoint measurements are related to severe cell damage such as tetrazolium reduction assay and lactate dehydrogenase (LDH) assay to detect viable cells and IL-1 release as inflammatory markers 21
Another principal function of the NADPH produced by ER-localized hexose-6-phosphate dehydrogenase is to provide the reducing energy to ER-localized reductases, specifically those involved in steroid hormone metabolism, with 11-hydroxysteroid dehydrogenase 1 (11-HSD1
Insights Imaging 8 (6), 537548
Sustained increases in iron or decreases in GSH suppress GPX4 levels thereby compromising cellular antioxidant defenses
Ratajczak, J
Optimizing timing helps on both fronts
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