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Ran S, Gao X, Ma M, Zhang J, Li S, Zhang M, et al

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Additionally, HSA-mediated ARKO in myocytes did not affect overload-induced hypertrophy, Type 2 fiber transition, maximal force production, or fatiguability of plantaris following synergist ablation of soleus and gastrocnemius in 12-16-week-old male mice [206]

The Phase 3 SYNCHRONIZE trials use extended, flexible dose escalation, which is expected to substantially improve tolerability

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