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It produces an unpleasant rancid butter smell

Additionally, with equivocal findings in DR and NAION, discussing personalized ocular risk of starting GLP-1RA in patients is key, and considering increased follow-up frequency after medication initiation may be warranted

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Berberine and its role in chronic disease

From a pharmacological perspective, tirzepatide acts primarily through GIP and GLP-1 receptor pathways to modulate insulin secretion, glucagon suppression, and appetite regulation