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In the aforementioned study from our group, adult mice with partial IGF-1 also displayed decreased expression of genes involved in lipid metabolism (ATP-citrate lyase, acetyl-CoA acyltransferase 1B, acetyl-CoA acetyltransferase 1) and cholesterol synthesis and transport (Both HMG-CoA reductase and synthase, LDL-related protein 1, proprotein convertase subtilisin/Kesin type 9), resulting in dyslipidaemia
GLP-1 receptor agonists: effects on cardiovascular risk reduction
Use of GLP-1 drugs for weight loss is common (as much as 12% of the population), but long-term adherence to the medications has been reported to be poor
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