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Key variants in genes like FTO (rs9939609), MC4R (rs17782313), GIPR (rs1800437) reveal how your body responds to GLP-1 therapy and weight loss, information that can help your fertility team understand your individual risk-benefit profile
Let's take 3 common examples for comparison
DOI 10.1038/s41591-022-02026-4 - separate 104-week randomized trial
GLP-1s primarily work by promoting insulin secretion and suppressing appetite, while MOTS-c works at a more fundamental cellular level by enhancing insulin sensitivity and energy expenditure
Selection should depend on donor characteristics, scalp laxity, graft requirements, hairstyle and scarring preferences, previous surgery, long-term donor planning and the surgeons competence
