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In people with kidney problems, diarrhea, nausea, and vomiting may lead to fluid loss (dehydration), which can worsen kidney problems

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Et tilfldigt fundet stof (exendin-4, exenatide), som blev isoleret fra spyttet i en gle fra Arizona, viste sig at bindes til GLP-1-receptoren og at have samme effekter som GLP-1, men det var stabilt overfor DPP-4 og blev elimineret langsommere i nyrerne

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