The rest of the MTs are encoded with single gene [31]
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2D two-dimensional hiPSC human induced pluripotent stem cell 3D three-dimensional hPSCs human pluripotent stem cells AAV adeno-associated virus HUVECs human umbilical vein endothelial cells ADPKD autosomal dominant polycystic kidney disease iETV2-hiPSCs inducible ETV2-expressing human induced pluripotent stem cells AI artificial intelligence iPSC induced pluripotent stem cell AKI acute kidney injury NF-B nuclear factor kappa-light-chain-enhancer of activated B cells ALI air-liquid interface NGAL neutrophil gelatinase-associated lipocalin cAMP cyclic adenosine monophosphate PBMCs peripheral blood mononuclear cells CKD chronic kidney disease pFSGS primary focal segmental glomerulosclerosis CRISPR/Cas9 clustered regularly interspaced short palindromic repeats/CRISPR-associated protein 9 ROS reactive oxygen species ECM extracellular matrix scRNA-seq single-cell RNA sequencing ESC embryonic stem cell TCBs T cell bispecific antibodies ESRD end-stage renal disease TGF-1 transforming growth factor beta 1 EZH2 enhancer of zeste homolog 2 VEGF vascular endothelial growth factor Glossary References 1

First, it's important to note that data from human clinical trials involving ipamorelin is extremely limited
Similarly, IRE1 dysregulation has been observed in tauopathies, PrD, and HD, highlighting its role in neurotoxicity, whereas ATF6 dysfunction exacerbates protein aggregation and has been linked to FTD and tauopathies
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