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Exposure was defined as at least one redeemed prescription in each 6month interval, which could have misclassified brief or minimal use as sustained use
Overall prescribing trends The study found that 2,185,238 patients were prescribed a GLP-1 RA between January 2019 and December 2025, with 11,194,909 total prescriptions during this period
It is absorbed into the oral mucosa and has a high bioavailability
Adding significant additional caloric restriction through keto in a person without significant fat stores creates genuine risk of lean mass loss, nutritional deficiency, and metabolic disruption
In addition, patients with a personal or family history of melanoma, numerous nevi, and/or atypical nevi should have total body skin examinations on a regular basis
doi: 10.3389/fmed.2024.1365183, 6
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