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Theres no way to tell whether a non-response is the product, the dose, or individual variability, and no clinician to call when something goes wrong
Different medications, even those in the same class, may have different side effects. Your healthcare provider can help determine whether adjusting your dose, slowing titration, or trying a different medication makes sense based on your symptoms and weight loss goals
Nat Protoc 8:24712482
The gradual dose escalation schedule is specifically designed to minimise these moving up doses too quickly is the main reason gastrointestinal side effects become difficult to manage
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