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Treatments may include: Personalized diet and exercise plans
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The phentermine portion helps reduce appetite, while topiramate may support fullness and reduce food cravings for certain people
Weight loss and metabolic changes : Substantial weight reduction alters body composition and fluid balance
Nature 475 , 2730 (2011)
However, this popularity and demand comes with risks
In mice fed Se deficient diets, testicular atrophy, reduced diameter of the seminiferous tubules, osseous metaplasia, and reduced spermatogenic activity were observed: no mitotic activity in spermatogonia, reduced the number of spermatogenic cell lines (including stem cells, pachytene spermatocytes, spermatids, and maturing sperms), and higher rates of abnormal morphology of sperm were found without difference in chromosomal abnormalities in spermatocytes (85, 100)
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