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Activated PSCs have an increased ability to synthesize and secrete ECM, leading to increased pancreatic fibrosis and -cell failure
The STEP 1 trial published results in the New England Journal of Medicine in February 2021, showing 14.9% weight loss at 68 weeks (Wilding et al., NEJM 2021)
Individual results vary considerably, and some women do better on Wegovy than on Mounjaro depending on their side effect profile, medical history and response to each medication
Landau-Kleffner syndrome with mitochondrial respiratory chain-complex I deficiency
Labiaplasty is a procedure that alters the size and presentation of the labia minora (inner folds) and/or labia majora (outer lips)
Patients may present with proximal renal tubular acidosis, distal renal tubular acidosis and chronic kidney disease
