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In patients with severe vitamin B12 deficiencyespecially those with megaloblastic anemia successful treatment rapidly reactivates the bone marrow
Zepbound carries the FDA indication for chronic weight management in adults with obesity or overweight with at least one weight-related comorbidity
It is a synthetic fragment of human growth hormone (amino acids 176-191), studied in research settings for its proposed role in fat metabolism
The sixth coordination site, the center of reactivity, is variable, being a cyano group (-CN), a hydroxyl group (-OH), a methyl group (-CH3) or a 5-deoxyadenosyl group (here the C5 atom of the deoxyribose forms the covalent bond with Co), respectively, to yield the four B12 forms mentioned above
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