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Sexual dimorphism in atherosclerotic plaques of aged mice

It is thought to have a major role in neurotoxicity as well as the induction of CYP450 enzymes

Methods We searched PubMed, Embase, Cochrane and ClinicalTrials.gov up until 27 October 2021 for randomised controlled trials with a duration of at least 12 weeks that compared once-weekly tirzepatide 5, 10 or 15 mg with placebo or other glucose-lowering drugs in adults with type 2 diabetes irrespective of their background glucose-lowering treatment

Elevated expression of asparagine synthetase (ASNS), which transfers an amide group from glutamine to aspartate for asparagine formation, is associated with resistance to asparaginase therapy in ALL (Lomelino et al., 2017)

The use of peptides in knee OA is still in its exploratory stages, but so far they are receiving enthusiastic feedback from the regenerative medicine community