You can read the abstract at Semaglutide and Cardiovascular Outcomes in Patients with Type 2 Diabetes
1 A separate two-year extension followed participants with a BMI of 35 or higher who completed the main trial and tolerated their dose
That means patients should be cautious about bold claims, especially claims that promise rapid healing, injury reversal, or guaranteed results
Moreover, fatty acids can impair mitochondrial function, as high concentrations of FFAs cause mitochondrial membrane depolarization and activate the mitochondrial permeability transition pore related to mitochondrial calcium overload
Phenols, such as hydroxytyrosol and oleuropein, have shown antioxidant properties in vitro and in vivo studies (Posadino et al., 2021)
Extended-use side effects are still being determined, but muscle wasting (or muscle loss), mental health concerns, and vision issues have been marked as key long-term side effects