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Galinski EA, Stein M, Amendt B, Kinder M

The discomfort is minimal and comparable to a small pinch

We used the model to test how sensitive the model is to the size of the NAC rescue dose

The 8 mg group in the Phase 2 trial achieved 22.8% body weight loss at 48 weeks

In amphetamine-induced stereotypy models (a pre-clinical model of schizophrenia-like conditions), DSIP normalised brain metabolism and MAO activity disrupted by long-term amphetamine treatment, establishing a role for adrenergic system normalisation as a mechanism of DSIPs neuroprotective activity

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