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It cannot replace a clinician's judgment

Use peptide therapy responsibly

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The extended activity duration increases the window during which adverse effects could manifest

Alternative pharmacotherapy options include other GLP-1 receptor agonists such as semaglutide (Ozempic, Wegovy) or dulaglutide (Trulicity), which share similar mechanisms and may be more affordable or accessible

however, our understanding of their mechanism of action is limited by the lack of structural information on activated and full-length receptors