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doi:10.1097/00004836-199312001-00014 36
CGRP enhances new blood vessel formation by promoting the expression of VEGF and HIF (hypoxia-inducible factor) in endothelial cells
Methylcobalamin helps regenerate damaged nerves and maintain the myelin sheath, while Pyridoxine and Nicotinamide support neurotransmitter function and cellular repair
Deeper improvements in tone and firmness often appear after 48 weeks of consistent use
Some clinics now offer combination protocols using both PRP and topical peptides
Future research should focus on refining these treatment modalities and expanding comparative studies to optimize B12 deficiency management strategies effectively
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