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Day 61 or thereafter if : If no additional glycemic control is needed, then maintain the dosage at 4 mg orally once daily

This approach helps reduce nausea, especially during the first 4-5 weeks of treatment or after any dose adjustments

Accordingly, we encourage the adoption of GLP-1RA plus SGLT2i combination therapy in patients with T2DM and established atherosclerotic cardiovascular disease (ASCVD) or multiple risk factors for ASCVD (i.e., age 55 years, overweight/obesity, dyslipidemia, hypertension, current tobacco use, left ventricular hypertrophy, and/or proteinuria)

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The current study differs from the study by Wong et al