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10.1016/j.neulet.2013.05.008 31 HimadriP.KumariS
The concept of the gut-brain-ear axis has emerged, linking imbalances in the gut microbiota (dysbiosis) to the development of hearing loss 38 , exposure to environmental noise stress 39 , and chronic tinnitus 28
Keap1-null mutation leads to postnatal lethality due to constitutive Nrf2 activation
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GIP (Glucose-Dependent Insulinotropic Polypeptide): Added with Tirzepatide, GIP co-activation enhances the glucose-lowering and fat-storage-reducing effects of GLP-1 activation
Tirzepatide activates GLP-1 and GIP receptors in brain regions that regulate sleep, arousal, and circadian rhythmparticularly the hypothalamus and locus coeruleus
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