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Fat and her colleagues recently published an FDA database analysis demonstrating that, while rare, reported adverse skin events associated with GLP-1 receptor agonists can include rash and pruritus highlighting the need for further research
Additional noncanonical nodes include EGFR transactivation and intersections with Wnt/-cateninTCF7L2 signaling implicated in proliferation and survival
Only semaglutide, tirzepatide, and liraglutide are FDA approved for weight loss, but all of these medications are approved to treat type 2 diabetes
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