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doi: 10.1016/J.TJNUT.2024.11.007 359 Landis-PiwowarKRIyerNR
Without a substantial change in UK medicines law or the development of a fully proven and licensed non-injectable alternative for malabsorption conditions like PA, the injection will remain a Prescription-Only Medicine
Gently swirl or roll the vial until powder is fully dissolved (do not shake vigorously)
Purity standards of 98% or higher via HPLC are appropriate for research use, with mass spectrometry confirmation of the correct molecular weight (9111.5 Da) recommended
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Because folate deficiency may predispose to hyperhomocysteinemia in heterozygotes for the CBS defect, transsulfuration defects might be combined with remethylation defects in patients with basal hyperhomocysteinemia (Lentz et al, 2000)
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