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People with higher starting BMI Individuals with BMI above 40 often see faster absolute weight loss in the early phases, simply because a higher body weight means a larger caloric expenditure even at rest, and the same percentage reduction in food intake creates a larger absolute caloric deficit

Exercise and microbiome diversity Regular physical activity is one of the most powerful ways to increase gut microbiome diversity, independent of diet or supplementation

Are comfortable with research-stage compounds

It may cause a modest scale weight increase of 2 to 4 pounds from water retention in muscle tissue, which is not fat gain

Potential benefits may include: Supports appetite regulation Supports metabolic health goals May provide an alternative treatment approach when clinically appropriate Supports a comprehensive physician-directed weight management program Your provider will determine whether this treatment option is appropriate based on your medical history, health goals, and clinical evaluation

These can support hydration and a smoother skin feel