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Two residues with shorter side chains (I7 P and A13 P ) in GIP further weakened its binding to GLP-1R, consistent with the distinct cross-reactivity features of GIP and GCG with GLP-1R 5,6
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This traceability is required under FDA drug serialization regulations and is a core part of Hospira's quality system
GLP-1 drugs are now available in Europe and China, where the number of obese and overweight people is projected to reach 790 million people by 2030
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