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showed that Lip-1 downregulates ferroptosis-related proteins and transcripts after trauma, prevents GSH depletion, reduces lipid peroxidation and iron accumulation, decreases neuronal death, and improves motor performance in TBI models (114)

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doi: 10.1007/s12020-024-03896-z, 55

Senescent tumor cells secrete a TGF--enriched senescence-associated secretory phenotype (SASP), which activates AKT-mTOR signaling, reshapes the TME, and promotes malignant progression under therapeutic pressure