Due to the increase in use, science may need time to catch up on the side effects as in, to determine both short-term and long-term side effects as the drugs are used for different conditions and for longer periods of time
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As for the incident patients, an increase from 1.8 patients/1000 inhabitants in 2019 to 7.4 patients/1000 inhabitants in 2023 could be observed (Table 1 (Panel B))
Manufactured by Novo Nordisk at a list price approaching $1,000 per month, Wegovy was also the drug that most patients associated with the GLP-1 weight loss revolution
However, the main concern for topical therapies is whether adequate drug concentrations could be accomplished at the targeted site (Twidwell and Levine, 2016)