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Prolonged use of Vitamin B6 (over 2 months) at high doses exceeding 1g/day can lead to severe peripheral neuropathy, with symptoms including unsteady gait and numbness in the hands and feet

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De vloeibare vorm heeft namelijk een aantal nadelen: ze zijn niet lang houdbaar, vereisen chemische aromas en moeten gekoeld worden, om er maar een paar te noemen