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How Long The Medication Remains Active
Once activated, T lymphocytes secrete pro-inflammatory cytokines such as interferon- (IFN-), interleukin-2 (IL-2), and tumor necrosis factor- (TNF-), which drive tissue damage
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It simultaneously decreases food intake through GLP 1 and GIP effects, improves metabolic efficiency through GIP activation, and increases energy expenditure through glucagon receptor stimulation
Mari A, Sallas WM, He YL, Watson C, Ligueros-Saylan M, Dunning BE, Deacon CF, Holst JJ, Foley JE
The incretin hormones GIP and GLP-1 are important substrates for DPP-4 action, while increased DPP-4 activity is associated with lower levels of GIP and GLP-1 [3]
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