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In January 2026, Dispatch announced FDA IND clearance for DISP-10, enabling a phase 1 clinical study in solid tumors

One small randomized controlled trial in 450 pregnant women in West Africa, without specified MTHFR genotype but at high risk for preeclampsia, found that supplementation with 15 mg of riboflavin daily was not effective in preventing the condition (29), but the study was likely underpowered to detect a significant effect

NAC is more commonly studied for this purpose, but the appropriate choice depends on dose, formula, evidence, safety and regulatory context

Retatrutide also has been shown to reduce A1C levels (which measures average blood sugar over the past three months) in people with type 2 diabetes

Drugs 2 (2), 266270

Rosen says