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In addition to these common side effects, some weight loss medications can have more serious risks

You're literally taking a medication that powerfully suppresses appetite through hormonal mechanisms

When assessing how large a factor nutrition and physical activity play in achieving weight loss, metabolism is easier to understand

We also understand the importance of affordability

Firstly, metformin inhibits mitochondrial complex 1, and this in turn may reduce the production of reactive oxygen species [85, 86], thought to be involved in cellular damage and mitochondrial dysfunction

Creating a calorie deficit is what ultimately leads to weight loss, and for some people, small daily changes like these can add up. But for people who have struggled to lose weight despite sustained efforts with diet and lifestyle changes, medication may provide the additional support they need