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Hence, cilofungin, an echinocandin B derivative with a 4-octyloxy benzoate side chain, was synthesized but was withdrawn from further studies due to poor water solubility and the toxicity of its co-solvent system containing 26% polyethylene glycol [160]
Raising testosterone with enclomiphene should theoretically improve bone density, though long-term data specifically on enclomiphene and bone outcomes is limited
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