In vitro co-immunoprecipitation and fluorescence polarisation assays have investigated the binding affinity of Proxofim for the p53 interaction domain, examining whether the DRI construct competitively displaces endogenous FOXO4 from the FOXO4-p53 complex in senescent fibroblast cultures
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Chu X, Li X, Zhang Y, Dang G, Miao Y, Xu W, et al
Data availability All observational data in this work are available through public data archives
Smirnoff N (2018) Ascorbic acid metabolism and functions: a comparison of plants and mammals