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Using isolated rat aorta, the researchers demonstrated that BPC 157 induced a concentration-dependent vasodilation that was endothelium-dependent and mediated by nitric oxide (NO)
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To establish a connection with the NO-system, l-NAME (5 mg/kg intraperitoneally) (worsening) and/or L-arginine (100 mg/kg intraperitoneally) (beneficial effect) were given alone or together
J Pharm Sci
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