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(2025) 17:eadv2106
This effect helps protect the kidneys and slow the progression of chronic kidney disease in people with type 2 diabetes
However, three factors may explain this discrepancy
Insulin resistance, postprandial GLP-1 and adaptive immunity are the main predictors of NAFLD in a homogeneous population at high cardiovascular risk
Semaglutide, a GLP-1 receptor agonist, enhances insulin secretion, reduces glucagon release, and slows gastric emptying, helping regulate blood sugar and curb appetite
Older glucose lowering therapies demonstrated efficacy with respect to achieving glycemic targets but lacked benefits for hard kidney or cardiovascular (CV) outcomes [1]
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