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Eli Lilly and Company Lilly's triple agonist, retatrutide, delivered weight loss of up to an average of 71.2 lbs along with substantial relief from osteoarthritis pain in first successful Phase 3 trial

Some studies suggest that GLP-1 agonists may reduce the risk of cardiovascular events, like heart attacks and strokes, which is especially beneficial for people with diabetes or metabolic syndrome

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See the full ranked guides: Phase 1: The Titration Period (Weeks 012) Initially, patients experience a titration period that typically spans 8 to 12 weeks