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Probiotics support the gut microbiome changes that occur on GLP-1 therapy

It is further hypothesized that elevated calcium levels inside the cell might stimulate the secretory vesicles within the somatotroph cells, potentially leading to the release of growth hormone into the bloodstream

The FDA has since approved a higher 2 mg maintenance dose of Ozempic, which was not part of this comparison

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This only makes the situation worse, as the high GH levels only further increase the already elevated insulin-like growth factor-1 (IGF-1) concentrations